Inhibiting TNF-α signaling does not attenuate induction of endotoxin tolerance
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چکیده
منابع مشابه
Inhibiting TNF-α signaling does not attenuate induction of endotoxin tolerance
Tumor necrosis factor-alpha (TNF-α) is a central mediator of inflammatory responses elicited by Toll-like receptor agonists, such as the Gram-negative bacterial outer membrane antigen lipopolysaccharide (LPS). TNF-α is responsible for altering vascular permeability and activating infiltrating inflammatory cells, such as monocytes and neutrophils. Interestingly, TNF-α has also demonstrated the a...
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ژورنال
عنوان ژورنال: Journal of Inflammation Research
سال: 2014
ISSN: 1178-7031
DOI: 10.2147/jir.s75037